BREAST MRI

Screen Saver 

Surmounting many of mammography's limitations-and posing a few of its own-screening breast MRI could be an imaging boon for women at highest risk for cancer.

By Michelle McDonough, MD

References

 1.      Smith, R.A., Duffy, S.W., Gabe, R., Tabar, L., et al. (2004). The randomized trials of breast cancer screening: What have we learned? Radiol Clin North Am, 42(5), 793-806.

2.      Horner, M.J., Ries, L.A.G., Krapcho, M., & Neyman, N., (eds). SEER Cancer Statistics Review, 1975-2006, National Cancer Institute. Bethesda, Md., http://seer.cancer.gov/csr/1975_2006, based on November 2008 SEER data submission, posted to the SEER Web site 2009.

3.      Duffy, S.W., Tabar, L., Chen, T.H.H., Smith, R.A., et al. (2007). Effect of mammographic service screening on stage at presentation of breast cancers in Sweden. Cancer, 109(11), 2205-12.

4.      Boyd, N.F., Guo, H., Martin, L.J., Sun, L., et al. (2007). Mammographic density and the risk and detection of breast cancer. N Engl J Med, 356(3), 227-36.

5.      Djulbegovic, B., Hozo, I., & Lyman, G.H. (2007). Estimating net benefits and harms of screening mammography in women age 40 to 49 years. Ann Intern Med, 147(12), 882.

6.      Chart, P.L., & Franssen, E. (1997). Management of women at increased risk for breast cancer: Preliminary results from a new program. CMAJ, 157(9), 1235-42.

7.      Tilanus-Linthorst, M.M., Obdeijn, I.M., Bartels, K.C., de Koning, H.J., et al. (2000). First experiences in screening women at high risk for breast cancer with MR imaging. Breast Cancer Res Treat, 63(1), 53-60.

8.      Brekelmans, C.T., Seynaeve, C., Bartels, C.C., Tilanus-Linthorst, M.M.A., et al. (2001). Effectiveness of breast cancer surveillance in BRCA1/2 gene mutation carriers and women with high familial risk. J Clin Oncol, 19(4), 924-30.

9.      Komenaka, I.K., Ditkoff, B.A., Joseph, K.A., Russo, D., et al. (2004). The development of interval breast malignancies in patients with BRCA mutations. Cancer, 100(10), 2079-83.

10.   Lakhani, S.R., Van De Vijver, M.J., Jacquemier, J., Anderson, T.J., et al. (2002). The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2. J Clin Oncol, 20(9), 2310-8.

11.  Kuhl, C.K., Schmutzler, R.K., Leutner, C.C., Kempe, A., et al. (2000). Breast MR imaging screening in 192 women proved or suspected to be carriers of a breast cancer susceptibility gene: preliminary results. Radiology, 215(1), 267-79.

12.   Stoutjesdijk, M.J., Boetes, C., Jager, G.J., Beex, L., et al. (2000). Magnetic resonance imaging and mammography in women with a hereditary risk of breast cancer. J Natl Cancer Inst, 93(14), 1095-102.

13.  Morris, E.A., Liberman, L., Ballon, D.J., Robson, M., et al. (2003). MRI of occult breast carcinoma in a high-risk population. AJR, 181(3), 619-26.

14.  Saslow, D., Boetes, C., Burke, W., Harms, S., et al. (2007). American Cancer Society Breast Cancer Advisory Group. American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography. CA Cancer J Clin, 57(2), 75-89.

15.  Warner, E., Plewes, D.B., Hill, K.A., Causer, P.A., et al. (2004). Surveillance of BRCA1 and BRCA2 mutation carriers with magnetic resonance imaging, ultrasound, mammography, and clinical breast examination. JAMA, 292(11), 1317-25.

16.  Kriege, M., Brekelmans, C.T., Boetes, C., Besnard, P.E., et al. (2004). Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predisposition. N Engl J Med, J351(5), 427-37.

17.   Leach, M.O., Boggis, C.R., Dixon, A.K., Easton, D.F., et al. (2005). MARIBS study group. Screening with magnetic resonance imaging and mammography of a UK population at high familial risk of breast cancer: a prospective multicentre cohort study (MARIBS). Lancet, 365(9473), 1769-78.

18.  Kuhl, C.K., Schrading, S., Leutner, C.C., Morakkabati-Spitz, N., et al. (2005). Mammography, breast ultrasound, and magnetic resonance imaging for surveillance of women at high familial risk for breast cancer. J Clin Oncol, 23(33), 8469-76.

19.  Lehman, C.D., Blume, J.D., Weatherall, P., Thickman, D., et al. (2005). International Breast MRI Consortium Working Group. Screening women at high risk for breast cancer with mammography and magnetic resonance imaging. Cancer, 103(9), 1898-905.

20.  Sardanelli, F., Podo, F., D'Agnolo, G., Verdecchia, A., et al. (2007). Multicenter comparative multimodality surveillance of women at genetic-familial high risk for breast cancer (HIBCRIT study): Interim results. Radiology, 242(3), 698-715.